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Yes, it is possible to use a DJ controller with a PC. Many DJ controllers are designed to work with DJ software on a computer, and they connect to the computer using a USB cable. The DJ software on the computer provides the audio and mixing capabilities, while the DJ controller provides the physical controls like jog wheels, faders, and buttons for cue points and effects. This setup is often used by DJs who want the tactile feeling of a traditional DJ setup but also want the advanced features and library management capabilities of DJ software. Some popular DJ controllers that work with PCs include the Pioneer DDJ-400, the Numark Mixtrack Pro 3, and the Denon DJ MC2000.